DisGeNET - a database of gene-disease associations

PPARG, peroxisome proliferator activated receptor gamma, 5468

N. diseases: 877; N. variants: 101

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs72551363

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C1720861
Disease:

Familial Partial Lipodystrophy, Type 3

0.800

GeneticVariation

UNIPROT

PPARG F388L, a transactivation-deficient mutant, in familial partial lipodystrophy.

12453919

2002

dbSNP:

rs72551363

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C1720861
Disease:

Familial Partial Lipodystrophy, Type 3

0.800

GeneticVariation

UNIPROT

A novel heterozygous mutation in peroxisome proliferator-activated receptor-gamma gene in a patient with familial partial lipodystrophy.

11788685

2002

dbSNP:

rs72551364

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C1720861
Disease:

Familial Partial Lipodystrophy, Type 3

0.800

GeneticVariation

UNIPROT

PPARG F388L, a transactivation-deficient mutant, in familial partial lipodystrophy.

12453919

2002

dbSNP:

rs72551364

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C1720861
Disease:

Familial Partial Lipodystrophy, Type 3

0.800

GeneticVariation

UNIPROT

A novel heterozygous mutation in peroxisome proliferator-activated receptor-gamma gene in a patient with familial partial lipodystrophy.

11788685

2002

dbSNP:

rs121909242

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0007102
Disease:

Malignant tumor of colon

0.700

GeneticVariation

UNIPROT

dbSNP:

rs1800571

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0028754
Disease:

Obesity

0.700

GeneticVariation

UNIPROT

dbSNP:

rs28936407

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0007102
Disease:

Malignant tumor of colon

0.700

GeneticVariation

UNIPROT

dbSNP:

rs1801282

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0011860
Disease:

Diabetes Mellitus, Non-Insulin-Dependent

0.900

GeneticVariation

GWASDB

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

24509480

2014

dbSNP:

rs1801282

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0011860
Disease:

Diabetes Mellitus, Non-Insulin-Dependent

0.900

GeneticVariation

GWASDB

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.

22885922

2012

dbSNP:

rs1899951

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0011860
Disease:

Diabetes Mellitus, Non-Insulin-Dependent

0.800

GeneticVariation

GWASDB

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.

22885922

2012

dbSNP:

rs13306745

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0428472
Disease:

Serum HDL cholesterol measurement

0.700

GeneticVariation

GWASDB

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

23063622

2012

dbSNP:

rs13306745

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0392885
Disease:

High density lipoprotein measurement

0.700

GeneticVariation

GWASDB

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

23063622

2012

dbSNP:

rs17036170

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0860207
Disease:

Drug-Induced Liver Disease

0.700

GeneticVariation

GWASDB

Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs.

22968431

2012

dbSNP:

rs17036321

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0428474
Disease:

Serum LDL cholesterol measurement

0.700

GeneticVariation

GWASDB

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

23063622

2012

dbSNP:

rs17036321

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.700

GeneticVariation

GWASDB

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

23063622

2012

dbSNP:

rs4135361

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.700

GeneticVariation

GWASDB

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

23063622

2012

dbSNP:

rs4135361

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0428474
Disease:

Serum LDL cholesterol measurement

0.700

GeneticVariation

GWASDB

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

23063622

2012

dbSNP:

rs7646510

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.700

GeneticVariation

GWASDB

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

23063622

2012

dbSNP:

rs7646510

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0428474
Disease:

Serum LDL cholesterol measurement

0.700

GeneticVariation

GWASDB

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

23063622

2012

dbSNP:

rs1801282

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0011860
Disease:

Diabetes Mellitus, Non-Insulin-Dependent

0.900

GeneticVariation

GWASCAT

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.

28869590

2017

dbSNP:

rs1801282

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0011860
Disease:

Diabetes Mellitus, Non-Insulin-Dependent

0.900

GeneticVariation

GWASCAT

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

24509480

2014

dbSNP:

rs1801282

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0011860
Disease:

Diabetes Mellitus, Non-Insulin-Dependent

0.900

GeneticVariation

GWASCAT

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

29632382

2018

dbSNP:

rs1801282

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0011860
Disease:

Diabetes Mellitus, Non-Insulin-Dependent

0.900

GeneticVariation

GWASCAT

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.

22885922

2012

dbSNP:

rs1899951

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0011860
Disease:

Diabetes Mellitus, Non-Insulin-Dependent

0.800

GeneticVariation

GWASCAT

Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.

30054458

2018

dbSNP:

rs10510418

Entrez Id:	5468
Gene Symbol:	PPARG

PPARG

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017